Fluvoxamine is used for:

Treating obsessive-compulsive disorder (OCD). It may also be used for other conditions as determined by your doctor.

Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI) type of antidepressant. It works by increasing the activity of a naturally occurring chemical in the brain called serotonin, which affects behavior.

Do NOT use Fluvoxamine if:

• you are allergic to any ingredient in Fluvoxamine
• you are taking alosetron, cisapride, cyproheptadine, dextromethorphan, fenfluramine and its derivatives, pimozide, astemizole, terfenadine, tramadol, l-tryptophan, a phenothiazine (eg, thioridazine), sibutramine, St. John's wort, or tizanidine
• you are taking or have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fluvoxamine :

Some medical conditions may interact with Fluvoxamine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have stomach bleeding, seizures, mania, or a history of suicidal thoughts or behaviors

Some MEDICINES MAY INTERACT with Fluvoxamine. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Cyproheptadine or risperidone because the effectiveness of Fluvoxamine may be decreased
• Anorexiants (eg, phentermine), buspirone, butyrophenones (eg, haloperidol), dextromethorphan, fenfluramine and its derivatives, l-tryptophan, linezolid, lithium, metoclopramide, MAO inhibitors (eg, phenelzine), selegiline, sumatriptan, tetracyclic antidepressants (eg, trazodone), or tramadol because serotonin syndrome (unexpected irritability, increased muscle tone, altered consciousness) may be increased
• Alosetron, anticoagulants (eg, warfarin), aripiprazole, aspirin, atypical antipsychotics (eg, clozapine), benzodiazepines (eg, diazepam), beta-blockers (eg, propranolol), butyrophenones (eg, haloperidol), carbamazepine, cisapride, cyclosporine, galantamine, H₁ antagonists (eg, astemizole, terfenadine), hydantoins (eg, phenytoin), lithium, methadone, mexiletine, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), nefazodone, phenothiazines (eg, thioridazine), pimozide, propafenone, risperidone, serotonin norepinephrine reuptake inhibitors (eg, atomoxetine), sibutramine, tacrine, tetracyclic antidepressants (eg, trazodone), theophylline, tizanidine, or tricyclic antidepressants (eg, amitriptyline) because the actions and side effects of these medicines may be increased
• Cisapride or sumatriptan because the effectiveness may be decreased by Fluvoxamine
• St. John's wort or trazodone because unexpected side effects may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fluvoxamine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fluvoxamine :

Use Fluvoxamine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Fluvoxamine comes with an additional patient information sheet called a Medication Guide. Read it carefully and reread it each time you get Fluvoxamine refilled.
• Fluvoxamine may be taken with or without food.
• Avoid eating grapefruit or drinking grapefruit juice while taking Fluvoxamine.
• Continue to take Fluvoxamine even if you feel better.
• Do not miss any doses. If you miss a dose of Fluvoxamine and you are taking 1 dose daily, take the missed dose if you remember the same day. If you miss a dose of Fluvoxamine and you are taking more than 1 dose daily, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Fluvoxamine.

Important safety information:

• Fluvoxamine may cause dizziness or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Fluvoxamine. Using Fluvoxamine alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Fluvoxamine will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
• Antidepressants can increase suicidal thoughts and behaviors in some children and teenagers. This risk may be higher in individuals with bipolar illness (also called manic-depressive illness), a family history of bipolar illness, or a history of attempting suicide. Pay close attention to changes in moods or actions, especially if changes occur suddenly. Contact your health care provider right away if any of the following effects occur or worsen: depression, anxiety, restlessness or irritability, panic attacks, thoughts or attempts of suicide, or other unusual changes in behavior or mood.
• Several weeks (up to 8 weeks) may pass before you feel the full effect of Fluvoxamine.
• If you drink more than 3 alcohol-containing drinks a day, do not take Fluvoxamine without first discussing it with your doctor.
• Fluvoxamine is not recommended for use in CHILDREN younger than 8 years of age. Safety and effectiveness in this age group have not been confirmed. Use Fluvoxamine with extreme caution in CHILDREN between 8 and 18 years of age.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Fluvoxamine , especially during the third trimester. Fluvoxamine is excreted in breast milk. Do not breast-feed while taking Fluvoxamine.

Do not suddenly stop taking Fluvoxamine without your doctor's approval. Stopping Fluvoxamine suddenly may cause serious WITHDRAWAL symptoms, including a state of feeling unwell or unhappy, abnormal skin sensations, agitation, anxiety, confusion, dizziness, sudden emotional swings, headache, inability to sleep, irritability, lethargy, nausea, or sweating. If use of Fluvoxamine is to be stopped, your doctor will gradually decrease the dose.

Possible side effects of Fluvoxamine :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Change in taste; changes in sexual function; chills; constipation; delayed ejaculation; diarrhea; dizziness; drowsiness; dry mouth; fatigue; flu-like symptoms; flushing; frequent urination; gas; headache; impotence; inability to have an orgasm; indigestion; lightheadedness; loss of appetite; nausea; nervousness; sweating; tiredness; tooth disorder; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bizarre behavior; difficulty swallowing; fast heartbeat; fever; impulsive behavior or other unusual changes in behavior; mental or mood changes (eg, agitation, panic, hostility, irritability); pounding in the chest; seizures; severe nervousness or anxiety; severe restlessness; sleeplessness; suicidal thoughts or behaviors; tremor; vision problems; worsening of depression.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Other Useful Information:

Radiation: 1. Rays of energy. Gamma rays and X-rays are two of the types of energy waves often used in medicine. 2. The use of energy waves to diagnose or treat disease.

Replantation: 1. Literally, the act of planting again. 2. In surgery, the restoration of any part of the body to its original site. Also known as reimplantation.

The Chinese surgeon Zhong Wei Chen (1929-2004) was the "father of replantation." Dr. Chen was the first to reattach a severed hand with success which he did in 1963. Dr. Chen also developed many microsurgical procedures including techniques for preserving severed extremities, reattaching amputated fingers and thumbs, reconstructing muscles and repairing nerves and blood vessels.

Rheumatism: Rheumatism is an older term, used to describe any of a number of painful conditions of muscles, tendons, joints, and bones.

Rheumatism conditions have been classified as either localized, regional, or generalized. Localized rheumatism conditions include bursitis and tendinitis. Regional rheumatism conditions include chest wall pain, temporomandibular joint pain, and myofascial pain syndromes. Generalized rheumatism conditions include fibromyalgia.

Another category of rheumatism is psychogenic rheumatism. With this term it is understood that the patient is reporting inconsistent pains of muscles and joints that do not correspond to true anatomy and physiology. The patient is felt to have underlying psychological causes for the symptoms.

Rheumatology: A subspecialty of internal medicine that involves the non-surgical evaluation and treatment of the rheumatic diseases and conditions. Rheumatic diseases and conditions are characterized by symptoms involving the musculoskeletal system. Many of the rheumatic diseases and conditions feature immune system abnormalities. Therefore, rheumatology also involves the study of the immune system. Classical rheumatology training includes 4 years of medical school, 1 year of internship in internal medicine, 2 years of internal medicine residency, and 2 years of rheumatology fellowship. There is a subspecialty board for rheumatology certification. The American College of Rheumatology is the official organization acting on behalf of the field of rheumatology in the United States.

T cell: A type of white blood cell that is of key importance to the immune system and is at the core of adaptive immunity, the system that tailors the body's immune response to specific pathogens. The T cells are like soldiers who search out and destroy the targeted invaders.

Immature T cells (termed T-stem cells) migrate to the thymus gland in the neck, where they mature and differentiate into various types of mature T cells and become active in the immune system in response to a hormone called thymosin and other factors. T-cells that are potentially activated against the body's own tissues are normally killed or changed ("down-regulated") during this maturational process.

There are several different types of mature T cells. Not all of their functions are known. T cells can produce substances called cytokines such as the interleukins which further stimulate the immune response. T-cell activation is measured as a way to assess the health of patients with HIV/AIDS and less frequently in other disorders.

T cell are also known as T lymphocytes. The "T" stands for "thymus" -- the organ in which these cells mature. As opposed to B cells which mature in the bone marrow.

Teleology: The study of the ultimate purpose of the design of something in nature.

For example, "what is the true purpose of the nose?" is a teleological question and, to say that all evolutionary changes occur for a definite purpose is a teleological explanation of evolution.

"Teleology" comes from ancient Greek roots but it (and teleological) did not enter English until the 18th century. It is a compound of the Greek "tele-, telos," meaning "end or purpose" + the ending "logos" meaning "the science or study of" = the study of the ends or purposes.

Testosterone: A "male hormone" -- a sex hormone produced by the testes that encourages the development of male sexual characteristics, stimulates the activity of the male secondary sex characteristics, and prevents changes in them following castration. Chemically, testosterone is 17-beta-hydroxy-4-androstene-3-one.

Testosterone is the most potent of the naturally occurring androgens. The androgens cause the development of male sex characteristics, such as a deep voice and a beard; they also strengthen muscle tone and bone mass.

High levels of testosterone appear to promote good health in men, for example, lowering the risks of high blood pressure and heart attack. High testosterone levels also correlate with risky behavior, however, including increased aggressiveness and smoking, which may cancel out these health benefits.

Testosterone may be given to treat medical conditions, including female (but not male) breast cancer, hypogonadism (low gonadal function) in the male, cryptorchism (nondescent of the testis into the scrotum), and menorrhagia (irregular periods).